PyQt6 Signals, Slots and Events
Events and signals in PyQt6 demonstrates the usage of events and signals. The examples connect a signal to a slot, reimplement an event handler, and emit a custom signal.
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You can connect a signal to a slot with PySide.QtCore.QObject.connect() and destroy the connection with PySide.QtCore.QObject.disconnect().
Signals and slots - Wikipedia
I mean you can connect many slots to a signal, and if a slot is deleted the signal will know. Basically just saying those things are important to any library you want to use, and make implementation of a GOOD signal/slot mechanism non-trivial.